A global virtual event dedicated to the latest cardio-renal-metabolic disease treatment strategies to support better patient outcomes
KDIGO and Translational Medicine Academy (TMA) in partnership with Radcliffe Cardiology are delighted to announce the return of e-SPACE Cardio-Renal-Metabolic (CRM) to be held 4–5 April 2025.
Cardiovascular-kidney-metabolic (CKM) health reflects the complex interplay among metabolic risk factors, diabetes, chronic kidney disease and the cardiovascular system, significantly impacting global morbidity and mortality. To address these challenges, TMA and KDIGO have launched the e-SPACE CRM programme, empowering clinicians worldwide to enhance patient outcomes.
The 2025 e-SPACE CRM conference will deliver free, cutting-edge virtual education, uniting global thought leaders in cardiology, nephrology and diabetology. Its multidisciplinary approach ensures a balance of global and regional insights while maximising geographical reach.
The programme features concise expert presentations, live panel discussions and interactive "meet the expert" sessions, offering participants the chance to engage directly with world-class faculty.
Building on the success of e-SPACE CRM 2024, which gathered 60 experts and over 2,000 healthcare professionals, the 2025 event aims to elevate professional development while advancing KDIGO’s mission to improve care for patients with kidney disease globally.
Guided by an esteemed international faculty and supported by TMA’s expertise in education delivery, e-SPACE CRM 2025 is set to be a leading online conference. The event will also be submitted for EBAC® accreditation.
Watch e-SPACE CRM 2024 on-demand here.
(Please note this programme is subject to change)
Day 1
Keynote Session
Cardiorenal Metabolic: CRM the Future
Enrique Caballero and Stefan Anker


Meet the Experts
Advancing Patient Care in Heart, Kidney and Metabolic Diseases: Practical Insights From the DCRM 2.0 Practice Recommendations
Shelley Zieroth, Yehuda Handelsman and Stefan Anker
Supported by an unrestricted educational grant from Boehringer Ingelheim



Plenary Session
Session 1 - Foundational Therapies in CRM
Chairs – Stephan von Haehling and Manisha Sahay
SGLT2 Inhibitors – Francesco Cosentino
MRAs – Joao Ferreira
GLP-1 RAs – Tina Vilsbøll
Panel Discussion




Meet the Experts
Improving Identification, Evaluation and Treatment of HF: Learning of REVOLUTION HF
Lisa Anderson and Antoni Bayés-Genís
Supported by unrestricted educational grant funding from AstraZeneca


Plenary Session
Session 2 - Overcoming Treatment Inertia in CRM Disease
Chair – Stefano del Prato and Yuhui Zhang
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The Cardiologist Perspective – Gianluigi Savarese
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The Nephrologist Perspective – Matthew Weir
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The Diabetologist Perspective – Julia Mader
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The Primary Care Physician Perspective – Jean Philippe Minart
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Panel Discussion






Keynote Session
KDIGO Guideline Updates 2025: Anaemia in CKD
David Wheeler and Stefan Anker


Meet the Experts
Iron Deficiency in Cardiorenal Disease: Interdisciplinary Crosstalk
Beatriz Fernandez-Fernandez, Stefan Anker and Iain Macdougall
Supported by an unrestricted educational grant from CSL Vifor



Plenary Session
Session 3 - Managing Key Parameters in CRM
Chairs – Jozine ter Maaten and Mitja Lainscak
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Potassium Levels – Patrick Rossignol
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Albuminaria – Shahzeb Khan
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NT ProBNPs – Antoni Bayés-Genís
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Low eGFR – Finnian McCausland
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Panel Discussion






Meet the Experts
Hyperkalaemia Management: Learning From REALIZE-K
James Burton and Gianluigi Savarese
Supported by unrestricted educational grant funding from AstraZeneca


Plenary Session
Session 4 - AOMs Clinical Experience
Chairs – Marc-Andre Cornier and Wei Ling Lau
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The Nephrologist View – Peter Rossing
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The Diabetologist View – Scott Isaac
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The Cardiologist View – Javed Butler
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Muscle-Wasting Associated With AOMs – Stefan Anker
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Panel Discussion






Meet the Experts
Cardiac Resynchronisation Therapy: A Cornerstone of Heart Failure Care
Chairs – Andrea Russo and Christophe Leclercq
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CRT: Still a Cornerstone of Heart Failure Care? – William Abraham
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Optimising CRT in Practice: Patient Selection, Timing and Post-implant Care – Wilfried Mullens
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CRT in HF: The Patient’s Perspective – Marc Bains, Cecilia Linde and Steven Macari
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Panel Discussion – All faculty (joined by Javed Butler)
Supported by Medtronic







Plenary Session
Session 5 - Managing HFpEF in 2025
Chairs – Alice Cheng and Nisha Bansal
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Diagnosis Best Practices – Ambarish Pandey
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Current Therapies in HFpEF – Jennifer Green
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Management of Patients With HFpEF and CKD – Nisha Bansal
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Future Therapies in HFpEF Perspective – Mark Petrie
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Panel Discussion





Meet the Experts
REPLAY: Advancing Patient Care in Heart, Kidney and Metabolic Diseases: Practical Insights From the DCRM 2.0 Practice Recommendations
Shelley Zieroth, Yehuda Handelsman and Stefan Anker
Supported by an unrestricted educational grant from Boehringer Ingelheim



Plenary Session
Session 6 - Inclusivity and Adherence in CRM Disease
Chairs – Dinushika Mohottige and Antonio Ceriello
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The Cardiologist Perspective – Anu Lala-Trindade
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The Nephrologist Perspective – David Mariuma
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The Diabetologist Perspective – Kamlesh Khunti
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Panel Discussion – Faculty will be joined by Ankeet Bhatt






Day 2
Meet the Experts
REPLAY: Improving Identification, Evaluation and Treatment of HF: Learning of REVOLUTION HF
Lisa Anderson and Antoni Bayés-Genís
Supported by unrestricted educational grant funding from AstraZeneca


Plenary Session
Session 7 - Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease
Chairs – Debbie Shawcross and Michael Böhm
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MASLD and CVD – Faiez Zannad
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Screening and Diagnosis – Nicholas Chew
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Management – Cyrielle Caussy
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Panel Discussion – Faculty will be joined by Andrew Coats






Special Session
PROVIDE Project
Plenary Session
Session 8 - Managing Heart and Kidney in Patients With T2D
Chair – Ahmed Bennis and Gloria Ashuntantang
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The Cardiologist Perspective – Cristina Gavina
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The Nephrologist Perspective – David Wheeler
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The Diabetologist Perspective – Antonio Ceriello
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Panel Discussion





Meet the Experts
REPLAY: Cardiac Resynchronisation Therapy: A Cornerstone of Heart Failure Care
Chairs – Andrea Russo and Christophe Leclercq
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CRT: Still a Cornerstone of Heart Failure Care? – William Abraham
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Optimising CRT in Practice: Patient Selection, Timing and Post-implant Care – Wilfried Mullens
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CRT in HF: The Patient’s Perspective – Marc Bains, Cecilia Linde and Steven Macari
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Panel Discussion – All faculty (joined by Javed Butler)
Supported by Medtronic







Meet the Experts
Practical Implementation of Non-steroidal Mineralocorticoid Receptor Antagonist to Reduce Cardiorenal Risk
Shelley Zieroth, Peter Rossing and Muthiah Vaduganathan
Supported by an unrestricted educational grant from Bayer



Plenary Session
Session 9 - The Role of Non-Steroidal MRAs in CRM
Chair – John McMurray and Susanne Nicholas
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Difference Between NS and Standard MRAs – Gerasimos Filippatos
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Non-Steroidal MRAs: The Evidence in 2025 – Muthiah Vaduganathan
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Initiating Treatment in Patients With Poor Kidney Function – Hiddo Heerspink
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Finerenone in Patients With Mildly Reduced or Preserved Ejection Fraction – Kieran Docherty
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Panel Discussion






Meet the Experts
Effective Patient Communication in Obesity and Cardiovascular
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Welcome and Introduction – Laurence Sherman
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The What, Why and How of Patient Communication – All faculty: Robert Kushner, Vicki Mooney and Laurence Sherman



Plenary Session
Session 10 - Anaemia and Iron Deficiency
Chairs – Ewa Jankowska and Wolfgang Winkelmayer
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Management of CRM Disease – Wolfgang Winkelmayer
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FAIR-HF 2 Results – Stefan Anker
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IV Iron Meta Analysis – Robert Mentz
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Future Perspectives – John Cleland
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Panel Discussion





Meet the Experts
REPLAY: Iron Deficiency in Cardiorenal Disease: Interdisciplinary Crosstalk
Beatriz Fernandez-Fernandez, Stefan Anker and Iain Macdougall
Supported by an unrestricted educational grant from CSL Vifor




Nisha Bansal
University of Washington, Seattle, US

Antonio Ceriello
IRCCS MultiMedica, Milan, IT

David Wheeler
University College London, London, UK

Shelley Zieroth
University of Manitoba, Winnipeg, CA
Faculty

William Abraham
The Ohio State University, Columbus, US

Lisa Anderson
St George’s Hospital, London, UK

Stefan Anker
Charité Campus Virchow-Klinikum, Berlin, DE

Gloria Ashuntantang
Yaoundé General Hospital, Yaoundé, CM

Marc Bains
HeartLife Foundation

Antoni Bayés-Genís
Hospital Germans Trias i Pujol, Barcelona, ES

Ahmed Bennis
Ibn Rochd University Hospital, Casablanca, MA

Ankeet Bhatt
Kaiser Permanente San Francisco Medical Center, San Francisco, US

Michael Böhm
Saarland University Hospital, Homburg, DE

James Burton
University of Leicester, Leicester, UK

Javed Butler
University of Mississippi Medical Center, Jackson, US

Enrique Caballero
Harvard Medical School, Boston, US

Cyrielle Caussy
Hôpital Lyon Sud, Lyon, FR

Alice Cheng
University of Toronto, Toronto, CA

Nicholas Chew
National University Health System, Kent Ridge, SG

John Cleland
University of Glasgow, Glasgow, UK

Andrew Coats
Monash University, Melbourne, AU

Marc-Andre Cornier
Medical University of South Carolina, Charleston, US

Francesco Cosentino
Karolinska Institute, Stockholm, SE

Stefano del Prato
University of Pisa, Pisa, IT

Kieran Docherty
University of Glasgow, Glasgow, UK

Beatriz Fernandez-Fernandez
Jiménez Díaz Foundation University Hospital, Madrid, ES

Joao Ferreira
University of Porto, Porto, PT

Gerasimos Filippatos
National and Kapodistrian University of Athens, Athens, GR

Cristina Gavina
University of Porto, Porto, PT

Jennifer Green
Duke Clinical Research Institute, Durham, US

Yehuda Handelsman
The Metabolic Institute of America, Los Angeles, US

Hiddo Heerspink
University Medical Center Groningen, Groningen, NL

Scott Isaac
Atlanta Endocrine Associates, Cumming, US

Ewa Jankowska
Wrocław Medical University, Wrocław, PL

Shahzeb Khan
Baylor Scott & White Health, Dallas, US

Kamlesh Khunti
University of Leicester, Leicester, UK

Robert Kushner
Northwestern University Feinberg School of Medicine, Chicago, US

Mitja Lainscak
General Hospital Murska Sobota, Murska Sobota, SI

Anu Lala-Trindade
The Mount Sinai Hospital, New York, US

Wei Ling Lau
University of California, Irvine, US

Christophe Leclercq
Hospital Pontchaillou of Rennes, Rennes, FR

Cecilia Linde
Karolinska Institute, Stockholm, SE

Ian Macdougall
King’s College Hospital, London, UK

Julia Mader
Medical University of Graz, Graz, AT

David Mariuma
University of Washington, Seattle, US

Finnian McCausland
Brigham and Women's Hospital, Boston, US

John McMurray
University of Glasgow, Glasgow, UK

Robert Mentz
Duke University, Durham, US

Jean-Philippe Minart
Jawa Production/Riviera CheckUp, Cannes, FR

Dinushika Mohottige
Icahn School of Medicine at Mount Sinai, New York, US

Vicki Mooney
European Coalition for People Living with Obesity

Wilfried Mullens
Hospital Oost-Limburg, Genk, BE

Susanne Nicholas
David Geffen School of Medicine at UCLA, Los Angeles, US

Ambarish Pandey
University of Texas Southwestern Medical Center, Dallas, US

Mark Petrie
University of Glasgow, Glasgow, UK

Giuseppe Rosano
St Georges Medical School, London, UK

Patrick Rossignol
CHRU de Nancy, Nancy, FR

Peter Rossing
Steno Diabetes Center Copenhagen, Herlev, DK

Andrea Russo
Cooper Medical School of Rowan University, Camden, US

Manisha Sahay
Osmania General Hospital, Hyderabad, IN

Gianluigi Savarese
Karolinska Institute, Stockholm, SE

Debbie Shawcross
King's College London, London, UK

Lawrence Sherman
Meducate Global

Jozine ter Maaten
University Medical Center Groningen, Groningen, NL

Muthiah Vaduganathan
Brigham and Women's Hospital, Massachusetts, US

Tina Vilsbøll
Steno Diabetes Center Copenhagen, Herlev, DK

Stephan von Haehling
University Medical Centre of Gottingen, Goettingen, DE

Matthew Weir
University of Maryland, College Park, US

Wolfgang Winkelmayer
Baylor College of Medicine, Houston, US

Faiez Zannad
University of Lorraine, Vandoeuvre-Les-Nancy, FR

Yuhui Zhang
Fuwai Hospital, Beijing, CN
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Review the burden of diabetes, kidney disease and heart failure including morbidity, excess mortality and reduced quality of life affecting individuals around the world
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Describe the complexity and interlink between the three conditions
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Discuss existing guidelines and best approaches for screening patients
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Review evidence-based management strategies for diabetes, cardiovascular disease, heart failure, kidney disease and obesity including SLGT2i, GLP-1RA, new non-steroidal mineralocorticoid receptor antagonists and other emerging therapies
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Foster cross-collaboration between other cardiorenal / metabolic specialists and primary care physicians and allied health care professionals in order to improve patients outcomes
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Cardiologists
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Nephrologists
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Diabetologists
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General Practitioners (GPs)
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HF Specialists
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Nurses, Pharmacists and other Allied Healthcare Professionals
Sponsors
If you’re interested in becoming an educational partner or sponsor at this event, please contact [email protected]
About KDIGO
KDIGO is a global organisation developing and implementing evidence-based clinical practice guidelines in kidney disease. It is an independent, volunteer-led, self-managed foundation incorporated in Belgium and accountable to the public and the patients it serves.
KDIGO’s mission is to improve the care and outcomes of patients with kidney disease worldwide through the development and implementation of global clinical practice guidelines.
For more information on KDIGO, please visit https://kdigo.org.
About Translational Medicine Academy
Our ambition at the Translational Medicine Academy® (TMA) is to bring medical findings from bench to bedside and into the working lives of physicians and the care of patients. In seeking to improve therapeutic approaches, TMA works with its International Scientific Advisory Board on Critical Mission Areas® of public health importance in domains where there are educational shortcomings among physicians and unmet healthcare needs among patients.
Gathered around a Scientific Advisory Board of experts, the Translational Medicine Academy is an international non-profit Foundation with headquarter in Basel, and offices in Paris, and the US. TMA’s funding includes private donations from individuals and educational grants from governments, non-governmental organizations and corporations.
For more information on TMA, please visit www.tmacademy.org.
About Radcliffe Cardiology
We are Radcliffe, a knowledge network for the cardiovascular community
We’re here to bring cardiovascular knowledge, insight and innovation to life for clinicians around the world, using our communications and creative expertise, our platforms and connections across the community to help transform theory into practice faster and more effectively.
We bring medical knowledge to life
From great science writing and smart journal editing, the curation of evidence based and peer-reviewed content, to engaging new formats that cut through the noise, we believe that communication is at the heart of great healthcare.
Our work is underpinned by 3 core principles:
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We build on the best science
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We work hands-on with our community
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We bring fresh thinking
Our promise is that we’ll equip you with the latest knowledge and skills you need, to do the best for your patients.
For more information on Radcliffe Cardiology, please visit www.radcliffecardiology.com.
Please contact [email protected] should you have any queries.